The following is an excerpt....
BASICS
Description
Local or systemic illness caused by brown recluse spider bite envenomation
Etiology
- Brown recluse spider (also known as fiddleback spiders) features:
- Appearance:
- Delicate body and legs spanning 10–25 mm
- Tan- to dark-brown with darker violin-shaped marking visible on the upper aspect of the head
- 3 pairs of eyes
- Found widely throughout the south-central part of the U.S.
- Habitat: Typically warm and dry locations indoors or outdoors such as wood piles, bundles of rags, cellars, under rocks, or in attics
- Bites are typically defensive
- Mechanism of toxicity:
- Venom is a complex cocktail of enzymes and peptides that:
- Binds to RBC and causes hemolysis
- Causes prostaglandin release and activates complement cascade
- Causes lipolysis and tissue ...
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