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BASICS
Description
- A rare but potentially lethal, acute, necrotizing infection involving the renal parenchyma, renal pelvis, and perinephric tissues caused by a gas-forming organism.
- Highest risk in those with diabetes and patients with obstructing renal or ureteral stones
- Mortality rates in described series range from 10–40%.
- Synonym(s): Renal emphysema, Pneumonephritis
Epidemiology
- Only a few hundred cases have been reported in the English literature since 1966.
- Female > Male (6:1)
- Most patients are >60
- Bilateral cases are very unusual but reported.
- The left renal unit is slightly more likely to be involved.
- No documented cases in children.
Risk Factors
- DM found in >80–90%:
- Poor glycemic control is common
- Urinary tract obstruction usually found in nondiabetic cases:
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