The following is an excerpt....
BASICS
Description
Idiopathic inflammatory disease of the alimentary tract that may present anywhere in the GI tract; most commonly found in the terminal ileum (60%), but may be limited to the colon in 15–20%, proximal small bowel 10%:
- Transmural disease
- May involve multiple regions of the intestine in between normal sections (skip lesions)
Epidemiology
Incidence
- Annual incidence of 3–7 cases per 100,000
- In US, more common in whites
- Predominant age: 15–25 years; 2nd, smaller peak in ages 55–65 years
- Female > Male
- 2–4 × increased risk in Ashkenazi Jewish ethnicity
Prevalence
20–100 per 100,000
Risk Factors
Cigarette smoking (2 × higher risk in smokers)
Genetics
- 15% of patients have 1st-degree relatives with inflammatory bowel ...
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