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Cutaneous T-Cell Lymphoma Updated 4/2011

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BASICS

  • Description
  • Epidemiology
  • Risk Factors
  • Pathophysiology
  • Etiology

DIAGNOSIS

  • Signs and Symptoms
  • Tests
  • Differential Diagnosis

TREATMENT

  • Medication (Drugs)
  • Additional Treatment

Ongoing Care

  • Follow-Up Recommendations
  • Patient Education
  • Prognosis
  • Complications
The following is an excerpt....
BASICS

Cutaneous T-cell lymphomas are a rare group of mature T-cell lymphomas presenting primarily in the skin. These diseases involve overlap of the disciplines of dermatology, medical oncology, and radiation oncology. Other than allogeneic stem cell transplant, there are no curative therapies for this disease (12,3,4,).

Description
  • A heterogeneous group of relatively uncommon extranodal non-Hodgkin lymphomas
  • This section focuses on mycosis fungoides (MF), the most common type of cutaneous lymphoma. For other subtypes, please consult the reference section.
Epidemiology
  • Median age at diagnosis is 55–60; however, it can occur in children and young adults (2).
  • Male:Female = 2:1 (2)
  • African American incidence greater compared to whites (2)
Incidence

0.4 cases per ...

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See Also
Images >
1
FIGURE 24-88. Mycosis fungoides. A. A 66-year-old woman presented with a 30-year history of erythematous scaly patches and plaques with telangiectases, atrophy, and pigmentation. B.The papillary dermis is expanded by an infiltrate of atypical lymphocytes. Lymphocytes with hyperchromatic nuclei infiltrate the thickened epidermis.Credit: Elder AD, Elenitsas R, Johnson BL, et al: Synopsis and Atlas of Lever's Histopathology of the Skin. Lippincott Williams & Wilkins, Philadelphia, 1999, p 2, clin. fig. IA1; p 163, clin. fig. IVE3; p 167,