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Cyclic Vomiting Syndrome Updated 4/2011

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BASICS

  • Description
  • Epidemiology
  • Risk Factors
  • General Prevention
  • Pathophysiology
  • Etiology
  • Associated Conditions

DIAGNOSIS

  • Signs and Symptoms
  • Tests
  • Differential Diagnosis

TREATMENT

  • Medication (Drugs)
  • Additional Treatment
  • Complementary and Alternative Medicine
  • In-patient Considerations

Ongoing Care

  • Follow-Up Recommendations
  • Diet
  • Patient Education
  • Prognosis
  • Complications
The following is an excerpt....
BASICS

Description

An idiopathic chronic functional GI disorder characterized by discrete, recurrent, stereotypical episodes of high-intensity nausea and vomiting lasting hours to days, separated by symptom-free intervals

Cyclic vomiting syndrome (CVS) has a phasic pattern with four distinct phases.

  • Interepisodic: Symptom-free period
  • Prodromal: Often marked by nausea + abdominal pain; able to take oral medications
  • Vomiting: Nausea, vomiting, and retching
  • Recovery: Nausea remits and patient has recovered appetite, strength, and energy.

Epidemiology

Incidence

Unknown

Prevalence
  • 0.04–1.9%
  • Whites more affected than other races
  • Predominant sex: Female > Male (55:45).
Risk Factors
  • Family history of migraine headaches
  • Depression
  • Anxiety
  • Chronic cannabis use
Genetics
  • Possible matrilineal inheritence
  • A3243G mitochondrial DNA mutation
  • Ion-channel mutations
General Prevention
  • Handwashing to ...

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