Diseases & Conditions >
This topic is from The 5-Minute Clinical Consult About our sources

Diabetes Insipidus Updated 4/2011

Email       Print Section  |  Print Topic       Add to My Favorites

BASICS

  • Description
  • Epidemiology
  • Risk Factors
  • Pathophysiology
  • Etiology
  • Associated Conditions

DIAGNOSIS

  • Signs and Symptoms
  • Tests
  • Differential Diagnosis

TREATMENT

  • Medication (Drugs)
  • Additional Treatment

Ongoing Care

  • Follow-Up Recommendations
  • Diet
  • Patient Education
  • Prognosis
  • Complications
The following is an excerpt....
BASICS
Description
  • A condition of intense thirst (polydipsia) and excessive urination (polyuria) owing to the kidneys' inability to conserve water as they filter blood.
  • Most commonly, this results from decreased pituitary secretion of vasopressin [central diabetes insipidus (DI)] or failure of response to vasopressin (nephrogenic DI).
  • Rarely, DI can be induced by pregnancy (gestational DI)
  • System(s) affected: Endocrine/Metabolic
Epidemiology
Incidence
  • 1/25,000 persons
  • May occur in 18.3% following transsphenoidal microsurgery
  • Causes of DI:
    • 30% idiopathic
    • 25% brain tumors (malignant or benign)
    • 16% head trauma
    • 20% after cranial surgery
Prevalence
  • Vasopressin deficiency may occur at any age.
  • Nephrogenic DI is usually manifest in infancy.
  • Nephrogenic DI is encountered in males more commonly, reflecting its X-linked mode ...

You must be logged in to fully access this content.

Sign In
Sign up for a 30-Day Free Trial

Sign up for a 30-Day FREE Trial now and receive access to all content.

Start free trial!

Have a book code?

Submit your book code to create your FREE standard account.