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Hyperparathyroidism Updated 4/2011

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BASICS

  • Description
  • Epidemiology
  • Risk Factors
  • General Prevention
  • Pathophysiology
  • Etiology
  • Associated Conditions

DIAGNOSIS

  • Signs and Symptoms
  • Tests
  • Differential Diagnosis

TREATMENT

  • Medication (Drugs)
  • Surgery
  • In-patient Considerations

Ongoing Care

  • Follow-Up Recommendations
  • Diet
  • Patient Education
  • Prognosis
  • Complications
The following is an excerpt....
BASICS

Description

An acute or chronic dysfunction of the body’s normal regulatory feedback mechanisms for parathyroid hormone (PTH):

  • Primary: Intrinsic gland dysfunction and abnormal regulation of PTH secretion by calcium causing excessive PTH secretion
  • Secondary: Gland hyperactivity that is a response to hypocalcemia, vitamin D deficiency, or renal failure
  • Tertiary: Autonomous hyperfunction in the setting of long-standing secondary hyperparathyroidism (HPT)

Epidemiology

Incidence
  • Predominant age: Primary: approximately 1/750
  • Predominant sex: Female > Male (3:1)
Prevalence

1/750 adults

Risk Factors

Renal failure, age, poor nutrition, and/or family history

Genetics

Familial forms are rare but include:

  • Multiple endocrine neoplasia (MEN) types 1 and 2: Patients with multiple gland hyperplasia in the absence of renal disease should be screened ...

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